O'Brien attended Brookline High School, where he served as the managing editor of the school newspaper, The Sagamore. O'Brien has three brothers and two sisters. 1931), is a retired attorney and former partner at the Boston firm Ropes & Gray. 1929), is a physician and professor of medicine at Harvard Medical School where he specializes in epidemiology. O'Brien was born on April 18, 1963, in Brookline, Massachusetts.
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